Spot-On Flea Drops for Cats

Kill Fleas on Cats

Adult cat fleas have permanently remain on their host. Once a host is acquired, the fleas will not leave unless they die or are dislodged.

Topical flea drops for cats typically contain both an adulticide and an insect growth regulator (IGR). The adulticide (fipronil, imidacloprid or dinotefuran) will kill adult fleas on the cat. The IGR (pyriproxyfen or methoprene) prevents female fleas from laying viable eggs and stops the development of eggs and larvae.

bayer advantage flea drops for catsvectra flea drops for catsfrontline plus flea drops for catssentry fiproguard flea drops for cats
Product NameBayer Advantage IIVectra Cats & KittensMerial Frontline PlusSentry Fiproguard Plus
Price$40$35$35$35
Size4 tubes3 tubes3 tubes3 tubes
ApplicationSqueeze-OnSqueeze-OnSqueeze-OnSqueeze-On
Use OnCatsCatsCatsCats
Cat Size5 to 9 lbs
more sizes available
2 to 9 lbs
more sizes available
over 1.5 lbs
more sizes available
over 1.5 lbs
more sizes available
Cat Ageover 8 weeksover 8 weeksover 8 weeksover 8 weeks
KillsEggs
Larvae
Adults
Eggs
Larvae
Adults
Eggs
Larvae
Adults
Eggs
Larvae
Adults
Active IngredientsPyriproxyfen
Imidacloprid
Pyriproxyfen
Dinotefuran
(S)-Methoprene
Fipronil
(S)-Methoprene
Fipronil
A.I. Concentration0.46%
9.10%
3.00%
22.00%
11.8%
9.8%
11.8%
9.8%
Dose Duration1 month1 months1 months1 months
Total Duration4 month3 months3 months3 months
Product Label
MSDS
FleaScore
Reviewsread reviews
on Amazon.com
read reviews
on Amazon.com
read reviews
on Amazon.com
read reviews
on Amazon.com
  • Prices are approximations based off of Amazon.com prices at the time of publishing.
  • FleaScores are based off of product details (price, size, active ingredients, etc), as well as reviews aggregated from 3rd party sources.
  • (S)-methoprene and pyriproxyfen are insect growth regulators and prevent immature flea stages from reaching adulthood.
  • Fipronil is a broad-spectrum insecticide that affects an insect’s central nervous system.
  • Imidacloprid and dinotefuran are insect neurotoxins, belonging to the neonicotinoids class of compounds similar to nicotine.

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