Using Advantage II for Dogs on cats

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QuestionsCategory: Flea Control ProductsUsing Advantage II for Dogs on cats
Oleg asked 2 years ago

I’ve been using Advantage for Dogs on cats for many years by purchasing the Dogs derivative and splitting it into smaller doses appropriate for my cat’s weight. This seemed to be a common practice with vets as the Active Ingredients of the Dogs and Cats derivatives were identical.
When Advantage II came out, I continued with the practice of using the Dog product on Cats only adjusting the dosage.
However, after a while, Bayer added a “Do not use on Cats” warning on the packaging of Advantage II for Dogs.
I can understand why Bayer would put such a warning from a marketing point of view. However, as the non-active ingredients are not listed on the packaging of either product, I’m not sure whether there might be another reason.
I was wondering if you had any insight on this question of using Advantage II for Dogs on Cats.
I look forward to hearing from you,

2 Answers
Adam Retzer Staff answered 2 years ago

Hey Oleg,

Sorry for the late response. I was having hosting server issues.

Before answering your question, I want to state that I don’t recommend off label use of any kind, for any medication.

You’re correct. The ingredients are identical in Advantage II for both cats and dogs. And they’re in the same concentrations. The main difference is the amount of product used. Make sure you’re applying the correct dosage, or toxicity problems will likely occur.

Here are the dosage charts:

I don’t think it’s necessarily a marketing tactic to label dog treatments with “Don’t use on cats”. It’s probably more of a safety/legal issue. If everyone did what you’ve been doing, I’m sure at least a handful would poison their pets by applying the wrong dosage through lack of diligence and care.

Additionally, while Advantage II doesn’t contain permethrin, many other flea products do (such as Advantix II). Permethrin is highly toxic to cats. This is probably another reason why Bayer doesn’t want pet-owners getting in the habit of swapping treatments.

Hope this was useful!


pglegjig replied 8 months ago

could you please post a dosage chart for cats using advantage II for dogs?

Adam Retzer Staff replied 7 months ago

I am not going to do this, because it can lead to confusion and a small portion of visitors may end up treating their pets with the wrong product or dosage. I don’t advise off-label use of any kind.

Dani answered 7 months ago

Oleg (or anybody else who may see this) please do not,  DO NOT use canine flea medications on a cat. Maybe people don’t know this but there ate a number of ingredients in canine flea medications that will kill your cat. Look up toxic shock syndrome in cats and you’ll see. This is a very expensive and often fatal condition where your cat will have seizures and need inpatient care from a veterinarian. Certainly not worth saving a few cents by buying the cheaper canine version if your beloved pet dies or you get the vet bill for thousands of dollars because your animal was in the hospital for a week. Please,  please do not use any amount of canine medication on a cat.