Kill Fleas on Dogs
Adult fleas are permanent ectoparasites. They have developed a persistent relationship with their hosts and will rarely leave of their own volition.
Topically applied spot-on flea drops for dogs typically contain both an adulticide and an insect growth regulator (IGR). The adulticide (fipronil, imidacloprid, permethrin or dinotefuran) will kill adult fleas on the dog. The IGR (pyriproxyfen or methoprene) will prevent female fleas from laying viable eggs.
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| Product Name | Merial Frontline Plus | Bayer K9 Advantix II | Bayer Advantage II | Vectra 3D |
| Price | $40 | $45 | $40 | $45 |
| Size | 3 tubes | 4 tubes | 4 tubes | 3 tubes |
| Application | Squeeze-On | Squeeze-On | Squeeze-On | Squeeze-On |
| Use On | Dogs | Dogs | Dogs | Dogs |
| Dog Size | 5 to 22 lbs more sizes available |
11 to 20 lbs more sizes available |
11 to 20 lbs more sizes available |
11 to 20 lbs more sizes available |
| Dog Age | over 8 weeks | over 7 weeks | over 7 weeks | over 8 weeks |
| Kills | Eggs Larvae Adults |
Eggs Larvae Adults |
Eggs Larvae Adults |
Eggs Larvae Adults |
| Active Ingredients | (S)-Methoprene Fipronil |
Pyriproxyfen Imidacloprid Permethrin |
Pyriproxyfen Imidacloprid |
Pyriproxyfen Dinotefuran Permethrin |
| A.I. Concentration | 8.8% 9.8% |
0.44% 8.80% 44.00% |
0.46% 9.10% |
0.44% 4.95% 36.08% |
| Dose Duration | 1 month | 1 months | 1 months | 1 months |
| Total Duration | 3 month | 4 months | 4 months | 3 months |
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| FleaScore |  |
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| Reviews |
- Prices are approximations based off of Amazon.com prices at the time of publishing.
- FleaScores are based off of product details (price, size, active ingredients, etc), as well as reviews aggregated from 3rd party sources.
- (S)-methoprene and pyriproxyfen are insect growth regulators and prevent immature flea stages from reaching adulthood.
- Pyrethrin is a natural insect neurotoxin. It is an organic compound derived from Chrysanthemum plants.
- Permethrin and other pyrethroids are synthetic derivatives of natural pyrethrin.
- Fipronil is a broad-spectrum insecticide that affects an insect’s central nervous system.
- Imidacloprid and dinotefuran are insect neurotoxins, belonging to the neonicotinoids class of compounds similar to nicotine.
